Safety study of Intrauterine Contraceptive Devices considering Asian population

Aishwarya G, Kalaiselvan V, Goyal RK, Mathur R

Delhi Pharmaceutical Sciences and Research University Pushp Vihar, Sec-III, MB Road, New Delhi, INDIA


The study was initiated with a VigiAccess search that revealed a lack of adverse events reported from copper devices. A specific lack of data from the Asian region was also observed, thus creating a need for new research. To further establish a stronghold on the existing data around the adverse events occurring due to IUCDs, a systematic review was performed. Through the systematic review and meta-analysis, it was observed that clear data needs to be reported to the relevant authorities and scientific organizations for sensitizing the healthcare workers about the adverse events relating to IUCD. In the systematic review, the time difference of 1 to 5 years was noted in 23% of the cases between insertion and removal, and in the project, most of the removals due to AE were observed between the period 6 months to 1.5 years. The trend was hence, narrowed down by both the type and time difference of device removal. From the prospective patient perspective assessment, it is quite obvious that the Indian population is becoming aware of both the different kinds of contraception available to them as well as its crucial details like adverse events. Further studies and knowledge transfer could prove fruitful in the effective usage of IUCDs as a medical device. Despite the occurrence of adverse events and slight discomfort associated with the device usage, the majority of the patients in the hospital were comfortable with the IUCD and were open to recommending the same to their acquaintance In conclusion, it can be positively said that IUCD does have its set of benefit-risk parameters that need to be understood and explained in the right light to both the physicians and patients. With the right amount of follow-up and medical counselling, IUCDs can be considered a very safe, cost-saving, and long-term option for contraception amongst others.   

Article ID: O0401019 (Suppl 1)   RA  Preprint
Received: 08/06/2022 
Accepted: 08/07/2022

Published: 08/08/2022